Glutathione 1500mg
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Specifications
- Compound
- Glutathione, reduced (GSH)
- Vial Size
- 1500 mg lyophilized
- Molecular Weight
- 307.32 Da
- Sequence
- Tripeptide — γ-Glu-Cys-Gly
- CAS Number
- 70-18-8
- Purity (HPLC)
- ≥ 99%
- Storage
- −20 °C lyophilized
Handling & reconstitution
Store lyophilized vials at −20 °C. Reconstitute with bacteriostatic water (BAC) at the dilution appropriate to your research protocol. Reconstituted solution stable at 2–8 °C for ~28 days.
Certificate of Analysis
Every batch is independently tested for HPLC purity and mass-spec identity confirmation. Batch-specific COAs are published on the website — browse the full archive in the COAs →
How it works
Mechanism of action.
A short breakdown of the receptor targets, signaling steps, and cellular effects reported in the peer-reviewed research literature.
What it is
The reduced form (GSH) of a tripeptide assembled from glutamate, cysteine and glycine. The glutamate link is an unusual γ-carboxyl bond, which is why the molecule resists ordinary peptidases; the free thiol on the cysteine residue is the reactive site the redox literature concerns itself with.
Where it binds
Not a receptor ligand. Published work describes it acting as a substrate and cofactor — principally for the glutathione peroxidase (GPx) and glutathione S-transferase (GST) enzyme families — cycling between reduced (GSH) and oxidized (GSSG) states through glutathione reductase and NADPH.
What research reports
In cell-culture and animal research the GSH:GSSG ratio is used as an index of oxidative state. Investigators have documented neutralization of hydrogen peroxide and lipid hydroperoxides, Phase II conjugation of electrophilic substrates, and regeneration of oxidized vitamins C and E.
Studied in
Peer-reviewed studies have used it in hepatocyte detoxification models, oxidative-stress and ischemia-reperfusion paradigms, and melanogenesis research examining tyrosinase activity.
Common questions
Frequently asked.
How is the compound shipped?
Orders ship via USPS in plain outer packaging (no product names visible). Most orders process within 1–3 business days after payment clears.
How should the lyophilized vial be stored?
Store lyophilized vials at −20 °C until reconstitution. Once reconstituted with bacteriostatic water, solution is stable at 2–8 °C for approximately 28 days. Protect from repeated freeze-thaw cycles.
Where can I verify the batch COA?
Every batch is HPLC-verified and mass-spec confirmed. Batch-specific Certificates of Analysis are published directly on our website — browse the full archive in the COAs, or search by the batch number printed on your vial label.
Do you offer returns or refunds?
Because our products are research chemicals, all sales are final. The single exception is damage in transit — if a vial arrives visibly damaged we will ship a replacement at no additional cost. Contact info@aminovitaresearch.com within 7 days of delivery with photographs and your order number.
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